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by Varonica Dixon, M.D. - Pediatrics
Menactra is a newly licensed vaccine for preventing meningococcal
disease. It is recommended for all 11-12 year olds and 15-16 year
olds as well as college freshman before they move into the dorms.
Meningococcal disease is a rare but serious bacterial infection
that strikes about 2,600 Americans every year. Approximately 10%
of them will die of sepsis or meningitis, the survivors may lose
limbs, hearing, or have other neurologic problems. The symptoms
begin like the flu, but rapidly progress and can kill a healthy
young person in less than 48 hours. Recent studies have shown that
15 - 20 year olds actually have a 20% mortality rate.
The recommendations take into account the phasing in of this vaccine
over the next 5 years. There cannot be enough vaccine produced to
vaccinate every 11-20 year-old in the U.S.
The new vaccine has several benefits over older vaccine (Menomune):
Menactra has improved duration of protection, it induces immunologic
memory, allows for a booster response, and reduces the carrier state.
The vaccine is a conjugated vaccine, similar to the ProHIB vaccine
introduced in 1987 which has reduced the incidence of invasive HIB
disease among young children by 98%. It wont prevent all disease,
but it is expected to reduce the number of cases by over 60%.
The most common adverse effects from the vaccine are pain, redness,
and induration at the site of injection, headache, fatigue, and
malaise. Menactra vaccine should not be given to persons with known
hypersensitivity to any component of the vaccine or to latex, which
is used in the vial stopper.
Now the difficult part, lets get all of the 11-12 and 15-16-year-olds
in for their physicals, so we can give them the good news that we
have one more vaccine for them! (I know theyll be thrilled;)
The other ways to reduce the chances of getting this infection are
to avoid smoking, drinking alcohol, and please, dont share
drinks with your friends!
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